The objectives of the Epidemic Control Preparedness Unit (ECPU) are to: (a) improve understanding of the epidemiology of cholera; (b) understand the factors that determine the seasonality of cholera in endemic areas; (c) develop models for the prediction of outbreaks; and (d) improve methods of intervention to slash epidemics. To achieve these objectives, the ECPU conducts (1) surveillance to study epidemiology and ecology of cholera at sentinel sites in Bangladesh in collaboration with environmental microbiologists; (2) epidemiological investigations of cholera outbreaks in collaboration with GoB health services to monitor occurrence, distribution of epidemic strains of V. cholerae O1 and O139 and related drug-sensitivity patterns.